On the nature of seizure dynamics

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August undefined, 2024

WebHere, we analysed seizure dynamics mathematically and established a taxonomy of seizures based on first principles. For the predominant seizure class we developed a generic model called Epileptor. As an experimental model system, we used ictal-like discharges induced in vitro in mouse hippocampi. We show that only five state variables … Web7 de fev. de 2024 · Our study sheds new light on the nature of phase transitions and fluctuations in seizure spreading dynamics. We expect it to play an important role in the development of closed-loop stimulation approaches for preventing seizure spread in pharmacologically resistant epilepsy.

On the modelling of seizure dynamics. - Abstract - Europe PMC

Webseizures, which arise when large regions of the brain produce un- in describing dynamical phenomena such as ferromagnetism, controlled, synchronous neural activity. Partial-onset seizures form lasers and superconductivity in physics (Cross and Hohenberg, Web19 de out. de 2024 · Several models are developed to describe the dynamics of seizure generation and termination 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41. These models … simple hunting bow

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Web11 de jun. de 2014 · Europe PMC is an archive of life sciences journal literature. Web21 de set. de 2024 · Considering the similarities between the resulting dynamics and some features of seizure-like activity observed experimentally 1,48,49,50, we study these transitions as theoretical approximations ... Web1 de ago. de 2024 · A change of dynamic regime of the system (from awake to seizure, for example) can be considered as a change of attractor. Either an attractor evolves (one disappears, one appears), or two attractors co-exist in the phase space, and the trajectory passes from one to the other, crossing a separatrix. simple hunting lease agreement

On the nature of seizure dynamics - Academia.edu

Loss of neuronal network resilience precedes seizures and …

Web29 de abr. de 2024 · Seizures were produced in Rhesus Macaques through the intracerebral injection of Penicillin. We found unique seizure-onset pattern variations in the seizure foci of each brain region, further... Web24 de abr. de 2024 · Epilepsy is widely accepted to be a disorder of brain networks, and a seizure may be seen as an expression of a dynamical system, of which semiology is an emergent property. A seizure is a dynamic process defined by spatial and temporal aspects, and semiology is likewise expressed as a dynamic process with … simple hung bathroom sinkWeb1 de abr. de 2024 · analysed seizure dynamics mathematically and established a taxonomy of seizures based on first principles. For the predominant seizure class we … rawnsley park station address

"Web11 de ago. de 2024 · Optimizing antiepileptic drug therapy is very challenging due to the absence of a reliable method to assess how brain activity changes between seizures. This work uses the Taxonomy of Seizure... " - On the nature of seizure dynamics

On the nature of seizure dynamics

On the modelling of seizure dynamics. - Abstract - Europe PMC

WebSeizures can occur spontaneously and in a recurrent manner, which defines epilepsy; or they can be induced in a normal brain under a variety of conditions in most … Web11 de abr. de 2024 · Chromatin is the physical substrate of the genome that carries the DNA sequence and ensures its proper functions and regulation in the cell nucleus. While a lot is known about the dynamics of ...

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Web27 de mar. de 2024 · Patient-Specific Seizure Detection Using Nonlinear Dynamics and Nullclines. Abstract: Nonlinear dynamics has recently been extensively used to study … Web23 de out. de 2024 · In the field of computational epilepsy, neural field models helped to understand some large-scale features of seizure dynamics. These insights however remain on general levels, without translation to the clinical settings via personalization of the model with the patient-specific structure.

Web26 de nov. de 2024 · The mechanism of seizure emergence and the role of brief interictal epileptiform discharges (IEDs) in seizure generation are two of the most important … Web7 de fev. de 2024 · The model. We model the dynamics of seizure spread in a network of interacting nodes. In the initial following sections, we focus on patient-specific finite-size …

WebThe focus of this paper is to investigate the dynamics of seizure activities by using the Epileptor coupled model. Based on the coexistence of seizure-like event (SLE), … Web13 de jun. de 2014 · Here, we analysed seizure dynamics mathematically and established a taxonomy of seizures based on first principles. For the predominant seizure class we …

Web1 de ago. de 2014 · And somewhat surprisingly, the vast majority of seizure onset-and offset patterns as observed on the EEG can be classified as corresponding to a set of these mathematical forms -highlighting some...

WebEpileptic seizure dynamics typically takes the form of regular or irregular temporal rhythms in the EEG. A rhythm is a repetitive event that is identified by visual inspection as standing out from normal background activity and being distinct from known physiological EEG rhythms like the occipital alpha rhythms. rawnsley park homesteadWeb1 de jan. de 2024 · However, in realistic conditions seizures spontaneously terminate within a few minutes. This can be explained by taking into account dynamics of other ion concentrations. Intracellular sodium ([Na +] i) progressively increases during a seizure episode due to spiking activity and the slow nature of Na + removal processes (Fig. 1b). simple hunter gathererWeb15 de mar. de 2024 · The average periodicity varies individually, but group trends (multidien seizure chronotypes) 58 include about-monthly periodicity of ~20–35 days 51 and more … rawnsley park station cabinsWeb2024 Transitions in information processing dynamics at the whole-brain network level are driven by alterations in neural gain. PLoS Comput. Biol. 15 , e1006957. rawnsley park station dog sittingWeb4 de mai. de 2024 · Author summary Much attention has been devoted to the mechanisms underlying epileptic seizures. However, so far, the morphology of how seizures start on electrographic recordings (i.e. the seizure onset pattern) has been neglected as a potential indicator of the underlying dynamic mechanism. In this work, we take a spatio-temporal … simple hurt and grievous hurt ipcWebHere, we analysed seizure dynamics mathematically and established a taxonomy of seizures based on first principles. For the predominant seizure class we developed a generic model called Epileptor. As an experimental model system, we used ictal-like … rawnsley park station campgroundWeb1 de ago. de 2014 · Here, we analysed seizure dynamics mathematically and established a taxonomy of seizures based on first principles. For the predominant seizure class we … rawnsley park station camping